Targeting JAKs in SLE would be a logical therapeutic option which can be studied further starting with trials to determine the safety, pharmacodynamics and efficacy of these drugs in SLE

Targeting JAKs in SLE would be a logical therapeutic option which can be studied further starting with trials to determine…

Here, we show that CBM activation in endothelial cells has an additional, unanticipated consequence in that the producing MALT1 dependent cleavage of CYLD triggers disruption of the endothelial barrier and causes collapse of microvascular structures

Here, we show that CBM activation in endothelial cells has an additional, unanticipated consequence in that the producing MALT1 dependent…

Multiple myeloma may be the second most frequent hematological malignancy in the western world and remains incurable, predominantly due to acquired drug resistance and disease relapse

Multiple myeloma may be the second most frequent hematological malignancy in the western world and remains incurable, predominantly due to…